In Django, database migrations are managed using Django’s built-in migration framework, which allows developers to modify the database schema without directly altering the database. When changes are made to models, running python manage.py makemigrations generates migration files that describe these changes, and executing python manage.py migrate applies them to the database, ensuring that the schema stays synchronized with the model definitions. Developers can check applied migrations using python manage.py showmigrations and inspect the SQL commands generated by a migration using python manage.py sqlmigrate <app_name> <migration_number>. If migration issues arise, Django provides options like --fake to mark migrations as applied without executing them. The migration framework enables smooth database version control, ensuring that structural modifications are systematically tracked while preserving data integrity, making Django’s database management highly efficient and scalable.